What is Transbronchial Lung Biopsy?
Transbronchial lung biopsy (TBLB) obtains small samples of lung tissue beyond the visible airways, through the bronchoscope. It is used to evaluate diffuse lung diseases and some peripheral lung lesions, sometimes with imaging guidance.
Why it is done
- Interstitial lung disease and sarcoidosis
- Peripheral lung nodules or masses in selected cases
- Unexplained diffuse lung shadows
Before the procedure
- Fasting for about 6 hours before the procedure (you will be given exact instructions)
- Inform the team about blood thinners, diabetes medicines and allergies — some medicines may need to be paused
- Blood tests and recent imaging (CT scan) are usually reviewed beforehand
- Bring a family member or friend to accompany you home
During the procedure
- Biopsy forceps are advanced into the target area of the lung
- Several samples are obtained
- Imaging guidance may be used where available
After the procedure
- You will be observed for a short period until the sedation wears off
- Avoid eating or drinking for about 1–2 hours, until the throat numbness settles
- A mild sore throat, cough or slight blood-streaked sputum may occur briefly
- Do not drive or operate machinery for the rest of the day after sedation
- Biopsy results usually take a few days; your follow-up will be scheduled
- A chest X-ray may be done afterwards to check for pneumothorax
Safety & risks
Bronchoscopy is generally a safe procedure. Possible risks include sore throat, transient fever, minor bleeding, low oxygen levels during the procedure and, rarely, pneumothorax (especially after lung biopsy). Your doctor will discuss the risks relevant to you before obtaining consent.
Preparation instructions may differ for individual patients — please follow the specific advice given at your consultation.